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Hole Depth » History » Revision 2

Revision 1 (Amber Herold, 04/23/2010 09:59 AM) → Revision 2/5 (Amber Herold, 04/27/2010 02:39 PM)

h1. Hole Depth 


 The hole depth node, is a set of tools to measure parameters needed to correlate the 
 intensity values of hole with (I) and without ice (I0) with the physical thickness of the ice. 
 The two intensity values gives the image contrast , c=ln(I0/I), that is used in Hole Finder 
 Node Class as the relative measurement of thickness. Since the actual calibration of contrast 
 against physical thickness is not yet written, we do not advise using this node unless you 
 plan to perform your own query and fit the values with the proper function outside 
 Leginon. 



 Required bindings for recieving images: 

 <highlights> 
 <simplelist type="vert"> 
 <member> This node at the moment stands alone and is used in post session 
 processing.</member> 
 </simplelist> 
 </highlights> 




 h2.    Image Selection 


 Each selected image type are for different measurement required for the correlation. 
 *    I0= Image of the area after the ice is burned recorded at the magnification and 
 defocus at which the contrast-thickness calibration is intended. 


 Relevent Image Control Panel- 


 *    PickHoles: Pick location and calculates mean intensity within given radius of 
 the the Picked position. 




 *    I= Image of the area before the ice is burned recorded at the magnification and 
 defocus at which the contrast-thickness calibration is intended. 


 Relevent Image Control Panel- 


 *    PickHoles: Pick location and calculates mean intensity within given radius of 
 the the Picked position. 




 *    Hole Untilt= Image of the a small patch of ice burned away from carbob support at 
 high magnification that is used to determine the radius of the burned cylindrical 
 hole. 


 Relevent Image Control Panel- 


 *    Original: File Entry. 


 *    Edge: Create Edge Image of the hole. 


 *    Template: Create Ring Template and correlate with the edge image to obtain 
 the radius of the cylindrical hole. 




 *    Hole Tilt= Image of the same area as "Hole Untilt" with the stage tilted to 
 reveal some separation of the two cylinder end projection or partial ocluded path by 
 one of the end projection. 


 Relevent Image Control Panel- 


 *    Original: File Entry. 


 *    Edge: Create Edge Image of the tilted hole. 


 *    Template: Using the tilt-projected ring template created from "Hole Untilt" 
 and the microscopic stage alpha angle of the tilted image to correlate with the 
 edge image to obtain the correlation peaks of the the two end of the 
 cylinder. 


 *    Threshold: Threshold the correlation image to reveal only the two main 
 peaks. 


 *    Blobs: Find the two thresholded peaks and calculates the depth of the hole 
 from the separation. 










 h2.    Image Control Panel 


 NOTE: To see the effects of Testing the settings for a particular Hole Depth step in 
 the Image Control Panel, the corresponding Hole Depth step Display must be enabled before 
 using the Test feature in that step's Display Settings. 



 h2.    Original 




 h2.    Display 


 To view the original input image without any image processing done to it, enable 
 this button. Enabling this button will disable/override the Edge, Template, and 
 Threshold Displays. 





 h2.    Display Settings 





 *    Original Image: File Entry = Enter the path and name of an MRC image that 
 matches the Image selection chosen in the node toolbar. The filename and path for 
 each type are stored separately. Only the chosen type will be displayed. 











 h2.    Edge 


 The purpose of the Edge step is to convert the original image into an "edge" image 
 where the edges of the holes in the image are enhanced against a black background. 



 h2.    Display 


 To view the Edge image, enable this button. Enabling this button will 
 disable/override the Original, Template, and Threshold Displays. 





 h2.    Display Settings 





 *    Low Pass Filter Sigma = Enter the sigma of the low pass filter applied to the 
 edge image. A value of 0 will not apply a low pass filter to the edge 
 image. 


 *    Edge Finding Threshold = Enter a reasonable intensity value that will enhance 
 the edges of the hole(s) in the edge image. 


 *    Test = Press this button to test/apply the LP sigma and Edge Finding 
 Threshold effects on the edge image. 











 h2.    Template 


 The purpose of the Template step is to cross correlate a template of the properly 
 sized holes against the edge image where the edges of the holes have been enhanced in the 
 previous step. Unlike in HoleFinder, this template is a tilt projection of the circular 
 ring. 



 h2.    Display 


 To view the Template image, enable this button. Enabling this button will 
 disable/override the Original, Edge, and Threshold Displays. 





 h2.    Display Settings 





 *    Use "phase | cross" correlation = to do this calculation. 


 *    Rings (Add|Edit|Delete) = Add|Edit|Delete the inner and outer hole (ring) 
 diameters in this section. Use the ruler tool while displaying the Edge image to 
 measure the average inner and outer hole diameter. Enter the average inner and 
 outer hole diameter in this section. 


 *    Low Pass Filter Sigma (for Phase Correlation only) = Enter a low pass filter 
 sigma that is used only when phase correlation is used in this step. 


 *    Tilt Axis = Enter the angle in degree the tilt axis is measured from the 
 y-axis of the image. Positive is counterclockwise. 


 *    Test = Press this button to test/apply the parameters that have been adjusted 
 in this step. 











 h2.    Threshold 


 The purpose of the Threshold step is to apply a threshold to the previous Template 
 image. It is in unit of correlation. The Threshold image should have dots that represent 
 the center of all the found holes. 



 h2.    Display 


 To view the Threshold image, enable this button. Enabling this button will 
 disable/override the Original, Edge, and Template Displays. 





 h2.    Display Settings 





 *    Threshold = Enter the Threshold value of a dot that represents the center of 
 a hole (relative to the value with the stdv shown for the correlation 
 image). 


 *    Test = Press this button to test/apply the Threshold to the template 
 correlation image. Only the dots hat represent the center of the holes should 
 appear. It is highly likely that dots not representing the center of a hole will 
 also appear. 











 h2.    Blobs 


 The purpose of the Blobs step in Hold Depth is not only to mark the center of the 
 thresholded image but also to calculate the depth of the hole from the two marked 
 locations. 



 h2.    Display 


 To view Blobs, either the Original, Edge, Template, or Threshold Displays must be 
 enabled. The Blobs that pass this step or manually picked will be shown with a turquoise 
 crosshair. 





 h2.    Display Settings 





 *    Border = The pixel value distance from the edge of the image where all 
 potential hole targets will be erased. 


 *    Max. blobs = The maximum number of hole targets or blobs at this point that 
 are allowed. If the number of blobs exceeds this number, the extra blobs will be 
 eliminated. 


 *    Max. blob size = The maximum size of a blob that is allowed to pass. This is 
 roughly the square of an average blob diameter. Use the ruler tool on the 
 Threshold image to determine the average diameter of a blob. 


 *    Find blobs / Calc depth= Press this button to test/apply the Blobs criteria 
 to the Threshold image and calculate the depth of the hole if 2 blobs are found. 
 If only 1 blob is found, the correlation peaks are considered unresolved and a 
 separation of 1 pixel is assumed in the depth calculation. 


 *    Calc w/ selections= Press this button to calculate the depth of the hole 
 using the two manually picked blobs.. 











 h2.    Pick Holes 


 The purpose of the step is to locate the burned position in either the images before 
 or after the burning and to calculate the mean intensity within given radius. 



 h2.    Display 


 To pick and calculate mean intensity of the Picked Holes, the Original Displays 
 must be enabled. The acquisition targets that pass this step will be shown with a green 
 crosshair. 





 h2.    Display Settings 







 *    Hole Statistics Radius = The radius in pixels of the holes (that pass the 
 lattice criteria) that will be used to determine each hole's statistics. 


 *    Hole Statistics Zero Thickness = The intensity value of an empty hole, i.e. 
 zero thickness intensity. 


 *    Shiftpicks = If a hole has been picked and tested from I0 image, pressing this 
 button with a I image loaded causes the current picks shift by the offset of 
 correlation peaks between I0 to I. 


 *    Test = Press this button to test/apply the zero thickness and radius criteria 
 to calculate the mean intensity of the picked hole. 




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